This must be the one of the biggest questions potential dog owners are asking. There are many known dog breeds. And a pure-bred dog is still the best candidate for adoption. For an experienced dog owner, breeds are their least concern. While different breeds of dogs require different levels of care and attention, their basics [...]
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Corticosteroids are the most widely used immunosuppressants in dogs and cats. Two drugs are frequently used: prednisone (or prednisolone), and dexamethasone. Prednisone is used for both induction and maintenance, whereas dexamethasone is typically used in the induction phase, and only brieftly. When dosing these agents, the clinician should bear in mind their relative potency: dexamethasone [...]
Cyclophosphamide (Cytoxan, Mead Johnson, Evansville, Ind) is a very effective immunosuppressive agent for inducing remission in dogs and possibly cats with IMDs. This drug is an alkylator anticancer agent, which appears to suppress cell-mediated and humoral immunity, as well as mononuclear-phagocytic function. It is activated and metabolized by the microsomal fraction of the liver and [...]